Eine Gute Tat – Biomolecular Modelling CoursePublished: June 17, 2019Today started with the third installment of Dr. Leonhard Henkes' “Eine Gute Tat” courses. Returning to the MINT Garage, Leonhard had the chance to meet seventeen 10th graders from across the school district. The majority of the nearly young adults were girls. Only two boys entered the course.With a high interest for biology and chemistry in general, they wanted to learn more about proteins, pharmacology and "how drugs work". In addition, Leonhard spoke about the current pharmacological revenue system, and how R&D works nowadays in labs and in silico. With skyrocketing software costs per month, long development cycles from the first hit to clinical phase III and the high investments of currently more than 2.5 $billion per drug, this was of high interest to the pupils.To get hands on, Leonhard used a professional software package for biomolecular modeling, which the software vendor agreed to provide for free in the context of our "Eine Gute Tat" program. Following Leonhard's tutoring, the pupils got familiar with the software. Then, everybody got deep into biomolecular modeling, the the excited students learned how the reaction of splitting up lactosis into glucosis and galactosis can be visualized at the binding site of lactamase.After this warm-up, the course went deeper into the subject matter - and learned how Aspirin is able to block the binding of prostaglandin to COX2. Last but not least, a virtual screening was done, allowing the pupils to make use of techniques like docking, to get a small ranking of their own molecular structures."The 5 hours were really well spent,", says Dr. Leonhard Henkes from the inhive Group. "Despite its importance in today's drug development, computational science is really underrepresented in our standard school agenda. It was great to see how much fun the pupils had - and how much everybody was able to learn in such a short amount of time."Who knows - maybe this inspired a talented young adult to seek a professional career in science? We certainly hope so.
inhive on pharmacovigilance this fallPublished: June 12, 2019
Our CEO Oliver Vettel is looking forward to this year's talk at the "ExpertFORUM Pharmacovigilance 2019" taking place in Mannheim, 21.11 - 22.11.2019 this year. "The conference has become a jour fixe for drug safety departments in the pharmaceutical industry", says Jessica Hüske, Conference Manager. For more information on speakers, topics and the agenda, check out the Forum's web site. In his talk, Oliver will share his experience on tackling current digitalization issues in this field. Join us in Mannheim!
Finalizing the Defect Analysis ActivitiesPublished: June 12, 2019
Defect analysis advisory for major aviation platform: when tackling complex infrastructures, traditional defect support doesn't cut it. For that reason, our aviation client approached us last year - asking us to get hands-on and provide skilled technical personnel for a Expert Defect Analysis team. As we are now wrapping up our activities one year later, we are looking back at a successful project. With our understanding of the underlying technology, our client was able to promptly analyze and sustainably address problems in the highly complex and distributed solution architecture. In wrapping up, we quote our client's team leadership: "Thanks for the perfect collaboration and provided service". We're always driven by the success of our clients - and like to say thank you as well!